To enable a different layout in a module, to your module.php for the module define a new layout like so

public function init(ModuleManager $mm)
    {
        $mm->getEventManager()->getSharedManager()->attach(__NAMESPACE__, 'dispatch', function($e) {
            $e->getTarget()->layout('admin/layout');
        });
    }

then within your module.config.php view_manager settings define the template

'view_manager' => array(
        'template_map' => array(
            'admin/layout'           => __DIR__ . '/../view/layout/cms.phtml',
        ),
        'template_path_stack' => array(
            __DIR__ . '/../view',
        ),
    ),

or you can define a direct path in your module.php without any template mapping i.e

public function init(ModuleManager $mm)
    {
        $mm->getEventManager()->getSharedManager()->attach(__NAMESPACE__, 'dispatch', function($e) {
            $e->getTarget()->layout('layout/admin');
        });
    }

This will load module/view/layout/admin.phtml when this module is run